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Airways-2 national clinical trial

30 August 2018


The James Paget recently took part in a large national clinical trial called Airways-2 and the primary results have now been published.

Thank you to all JPUH clinicians and trial participants who took part.  Full details are available in the Journal of the American Medical Association (JAMA):  Effect of a Strategy of a Supraglottic Airway Device vs Tracheal Intubation During Out-of-Hospital Cardiac Arrest on Functional Outcome, The AIRWAYS-2 Randomized Clinical Trial.

 An info graphic giving details of the cardiac arrest Airway trial

 An  info graphic showing interventions received and patient outcomes

The trial found no significant difference between tracheal intubation and the i-gel supraglottic airway device (SGA) in functional outcome at hospital discharge or 30 days after an out of hospital cardiac arrest in adults. However, some differences were noted in the secondary and pre-specified sensitivity analyses.

Professor Benger, the lead author of the paper talks about the findings of the trial and the possible implications are for cardiac arrest management in this podcast